if PCAnywhere 12.0 has incompatibility issues with vista i don't think it is gonna run if u remove the check
maybe.. it will install but not run properly
try searching the other way round :
try getting a PCAnywhere version for Vista (i donno if they released it yet )
i think there is a Beta for vista called PCAnywhere 12.1
"If anyone is looking for a version of pcAnywhere that will run on vista you can find a beta of version 12.1 here:
http://www.symantec.com/home_homeoffice/products/download.jsp?pcid=pf&pvid=pca121beta
Keep in mind it is beta, but I installed it and it works fine on my vista pc. I even copied all my old remote connections into it and they work.
"